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Welcome to the ASCT Viewpoint
Welcome to the first issue of ASCT Viewpoint, an electronic newsbrief that will deliver ASCT news, upcoming events and selected articles related to our profession and the interests of our members.
Viewpoint will be delivered twice per month. Feel free to send me your feedback, comments and topics of interest at
SNGiroux@gmail.com.
Sandy Giroux
ASCT PR Chair
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Seattle Scope: ASCT's 2012 conference
Roxanna Alejandra Abrines
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ASCT's Conference in Seattle, Wash., this year was an incredible experience as a current cytotechnology student in training. All of the committees and staff involved in setting up and organizing the event were more than willing to open up a world of cytology to a new student's perspective of the field and its everchanging "morphology" taking on a myriad of shapes.
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UPCOMING EVENTS
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The Cytology Association of Alabama
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Birmingham, Ala.
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July 28
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Details to be announced.
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ASCT Educational Webinar:
New Cervical Cancer Screening Guidelines: What do they mean for me?
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Your PC
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July 31, 2 p.m. EST
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Ann T. Moriarty M.D., Co-Chairman, Work Group 6
Looking to the Future - Potential Impact of Molecular Screening
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Register
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Researchers find origin cells for cervical cancer
AFP via Google
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Researchers have found the cells at the origin of cervical cancer, in a discovery that could offer new ways to prevent and treat the disease, according to a U.S.-published study recently. Most cases of cervical cancer are known to be caused by specific strains of human papillomavirus, but now researchers know the specific group of cells that HPV targets, said the study in the Proceedings of the National Academy of Sciences.
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RLIP76 contributes to pancreatic cancer cell resistance to chemotherapy, radiation
Medical Xpress
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Researchers at the City of Hope Comprehensive Cancer Center in Duarte, Calif., have not only identified a protein that allows pancreatic cancer cells to resist therapy but also developed a way to block it, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference.
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Nanoparticle delivers chemotherapy directly to multiple myeloma, prevents CAM-DR
Genetic Engineering & Biotechnology News
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A nanoparticle that can deliver chemotherapy drugs directly to multiple myeloma cells and overcome cell-adhesion-mediated drug resistance is reported by researchers at the University of Notre Dame in Indiana. The micellar nanoparticles carry both doxorubicin and peptide antagonists of very late antigen-4, a cell surface protein expressed on MM cells that plays a key role in mediating the adhesion of MM cells to bone marrow stroma, which is implicated in the development of CAM-DR.
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Gene expression classifier identifies which 'indeterminate' thyroid nodules are benign
Family Practice News
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A novel gene expression classifier was successful in determining which "indeterminate" thyroid nodules are benign and which were "suspicious" in a prospective, multicenter trial. Following fine-needle aspiration analysis, 15-30 percent of thyroid nodules are not clearly benign or malignant. These cytologically indeterminate nodules (including atypia or follicular lesions of undetermined significance and lesions suspicious for follicular/Hurthle cell neoplasm) are often referred for diagnostic surgery, which proves three-fourths to be benign, Dr. Richard Lanman, chief medical officer at Veracyte Inc., said at the annual meeting of the American Association of Clinical Endocrinologists in Philadelphia.
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International survey on laboratory safety launched
Nature (blog)
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The death of Sheharbano Sangji in 2008, following a fire in the chemistry department at UCLA, triggered calls to improve academia's safety standards not just at UCLA, but across the United States. Similar concerns were voiced last year when a young undergraduate student, Michele Dufault, died at Yale University. And when the U.S. Chemical Safety Board reviewed the state of academic lab safety after a non-fatal accident at Texas Tech University in Lubbock in 2009, it concluded that "Safety practices at U.S. universities leave a lot to be desired."
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A hard look at soft cancers
Daily Rx
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Faced with little data on a rare cancer, a surgeon specializing in soft tissue sarcomas, a fairly rare cancer, has published a predictive chart to help oncologists understand all of the treatment options. Although soft tissue sarcomas are rare, some are completely unaffected by standard treatments.
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Breast cancer chemotherapy resistance — genes identified
Medical News Today
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Chemotherapy before surgery is not always effective against some tumors. Now, a study published in Nature Medicine reveals that researchers at Vanderbilt-Ingram Cancer Center have identified a gene expression pattern associated to resistance to breast cancer chemotherapy. In addition, the study findings suggest new treatment options for individuals with specific subtypes of breast cancer.
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Hematology pipeline: Baby steps after a giant leap
OncLive
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There are thousands of clinical studies in progress for hematologic malignancies, but many are in phase I or II trials, so it may be some time before the most promising compounds add new weapons to the hematology armamentarium, where they are sorely needed.
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Scientists discover mechanism that promotes lung cancer growth, survival
Virginia Commonwealth University via MedicalXpress
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A multi-institutional research study has uncovered a new mechanism that may lead to unique treatments for lung cancer, one of the leading causes of death worldwide. The scientists discovered that the protein Bax Inhibitor-1 protects lung cancer cells and promotes tumor growth by regulating autophagy, a complex process initiated under stressful conditions that breaks down a cell's own components to provide nutrients needed for survival.
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Smoking tied to one type of skin cancer
Fox News
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Smoking may not only cause wrinkles and sagging skin, it might also increase risk of one type of skin cancer, researchers suggest in a new report. Studies have linked smoking to a long list of health effects, including heart disease and lung cancer, but the evidence has been mixed for skin cancer.
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Tending the body's microbial garden
The New York Times
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For a century, doctors have waged war against bacteria, using antibiotics as their weapons. But that relationship is changing as scientists become more familiar with the 100 trillion microbes that call us home – collectively known as the microbiome. "I would like to lose the language of warfare," said Julie Segre, a senior investigator at the National Human Genome Research Institute. "It does a disservice to all the bacteria that have co-evolved with us and are maintaining the health of our bodies." This new approach to health is known as medical ecology.
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