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INDUSTRY NEWS

Implementation Science to Address Health Disparities During the Coronavirus Pandemic
Co-authored by Khadijah Breathett (with Karla I. Galaviz, Jessica Y. Breland, Mechelle Sanders, Alison Cerezo, Oscar Gil, John M. Hollier, Cassondra Marshall, J. Deanna Wilson, and Utibe R. Essien)

Implementation science can help address disparities by guiding the equitable development and deployment of preventive interventions, testing, and, eventually, treatment and vaccines. In this study, the authors discuss three ways in which implementation science can inform these efforts: (1) quantify and understand disparities; (2) design equitable interventions; and (3) test, refine, and retest interventions.

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Importance of Housing and Cardiovascular Health and Well-Being: A Scientific Statement From the American Heart Association
Co-authored by Khadijah Breathett (with Mario Sims, Kiarri N. Kershaw, Elizabeth A. Jackson, Lisa M. Lewis, Mahasin S. Mujahid, and Shakira F. Suglia)

Housing is a major social determinant of cardiovascular health and well-being. This statement summarizes research that highlights important pathways by which dimensions of housing affect cardiovascular health and general well-being. This statement also shows that there are gaps in the scientific literature on housing and health and identifies areas that need further exploration.

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Progression of Infarct-Mediated Arrhythmogenesis in a Rodent Model of Heart Failure
Co-authored by Ikeotunye R. Chinyere (with Talal Moukabary, Mathew D. Hutchinson, Jordan J. Lancaster, Elizabeth Juneman, and Steven Goldman)

Heart failure (HF) post-myocardial infarction (MI) presents with increased vulnerability to monomorphic ventricular tachycardia (mmVT). To appropriately evaluate new therapies for infarct-mediated reentrant arrhythmia in the preclinical setting, chronologic characterization of the preclinical animal model pathophysiology is critical. This study aimed to evaluate the rigor and reproducibility of mmVT incidence in a rodent model of HF.

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ADDITIONAL UPDATES

Maternal Morbidity and Mortality: Are We Getting to the "Heart" of the Matter?
Co-authored by Patrice Desvigne-Nickens (with Jasmina Varagic, Joyonna Gamble-George, Lisa Hollier, Christine Maric-Bilkan, Megan Mitchell, Victoria L. Pemberton, and Nicole Redmond)

In this review article, the authors highlight new advancements in understanding adverse, pregnancy-related CV conditions and will discuss promising strategies or interventions for their prevention, diagnosis, and treatment.

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Trends in Hypertension Clinical Trials Focused on Interventions Specific for Black Adults: An Analysis of ClinicalTrials.gov
Co-authored by D. Edmund Anstey and Olugbenga Ogedegbe (with Alexander R. Zheutlin, David Caldwell, Molly B. Conroy, and Adam P. Bress)

Black adults in the United States face greater rates of cardiovascular disease, largely mediated through higher prevalence of hypertension compared with White counterparts. However, race is not a discrete biological category, but a social construct. This categorization impacts trial recruitment, retention, and environmental interactions, all of which impact clinical response to medical interventions.

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