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April 18, 2019
News From Medscape
The following recommended articles on are freely available through the partnership between ABC and Medscape, no registration or login required.
Continuing ARB Recalls Shake Up Hypertension, HF Care
Concerns over ongoing recalls of angiotensin II receptor blockers (ARBs) are forcing physicians and patients to choose between optimal treatments and rattling confidence in the safety of the generic drug supply itself.
Telehealth, Urgent Care, Retail Clinics Getting More Popular
The use of alternative places of health service, such as telehealth, retail clinics, urgent care clinics, and emergency rooms, has grown rapidly over the past decade, a new report from the independent, nonprofit research firm FAIR Health shows.
Physicians' Understanding of Disability Law Lacking
Many physicians may have an incorrect or only superficial understanding of their legal responsibilities for accommodating patients with disabilities, a population that's poised to grow with the aging of baby boomers, according to the authors of a newly published study.
US Influenza Activity Dipping but Still High, CDC Reports
Influenza activity fell slightly but "remains relatively high for this time of year," according to the Centers for Disease Control and Prevention (CDC). Influenza activity has been at or above baseline levels for 18 weeks in the United States compared with 16 weeks for the last five seasons, the CDC said in a March 29 report for the week ending March 23 (week 12).
Items of Interest
Stress Coincides With Worse Cardiovascular Health in Black Americans
By Dapo Iluyomade, MD
Psychosocial stressors lead to poorer CVH -- and black Americans suffer from worse CVH than whites. It seems intuitive for one to ponder, especially in the current sociopolitical state of the country, whether poorer CVH in blacks is potentially secondary to significantly more psychosocial stress than that faced by other demographics.
In African Villages, These Phones Become Ultrasound Scanners
The Butterfly is about the size of an electric shaver. It is battery-powered and contains microchips rather than piezoelectric crystals, so it usually won’t break if dropped.
Minority Health Matters
April is National Minority Health month, and to shed a spotlight on minority health, PhRMA’s Courtney Christian wrote a blog piece focused on raising awareness on health disparities that affect ethnic and racial minority populations.
Op-Ed: Congress Should Adopt Solutions to End Minority Health Disparities
Cardiologist Foluso Fakorde writes: Since April is National Minority Health Month, now is the perfect time to reflect on the inequities facing millions of Americans, as well as how we can collectively pave the path for building stronger, healthier communities.
The Healthline & NAMI Stronger Scholarship
The numbers are staggering. An estimated 322 million people around the world live with depression. Over 44 million American adults have a mental health condition, and only 41% of those have received treatment in the last year. Recent reports indicate that depression is one of the greatest mental health challenges facing Americans today.
This year, Healthline is dedicating its annual scholarship funds to four outstanding students working to change the face — and future — of mental health.
Featured Articles by Members
ABC Members: We welcome your published research submissions and articles for inclusion in future issues of Clinical Updates and Insights. Email Rachel Williams at and please attach file or include links to the original published work and/or abstract.
Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study
Co-authored by Samuel Dagogo-Jack (Barbara H. Braffett, Ionut Bebu, William I. Sivitz, Mary Larkin, Orville Kolterman and John M. Lachin, on behalf of the DCCT/EDIC Research Group)
The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study demonstrated the beneficial effects of intensive therapy on atherosclerosis and clinical cardiovascular disease (CVD) outcomes. The current analyses evaluated the relationship between longitudinal changes in insulin dose and CVD risk factors and outcomes.
Diabetes Self-Management Education for Special Populations: The Social Determinants of Health Matter
Co-authored by LaPrincess C. Brewer, MD, MPH (Lisa A. Cooper, MD, MPH, Christi A. Patten, PhD)
Although imperative, imparting knowledge to patients may not be sufficient for successful diabetes self-management. Thus, incorporation of other factors and support mechanisms beyond didactic education is necessary. Health care providers and experts in DSME agree that transformation of our current programs at the individual and systems levels with a focus on prioritizing at the social determinants of health is warranted.
Potential Role of Metal Chelation to Prevent the Cardiovascular Complications of Diabetes
Co-authored by Gervasio A Lamas, MD (Rossana Calderon Moreno, MD Ana Navas-Acien, MD PhD Esteban Escolar, MD David M Nathan, MD Jonathan Newman, MD John F Schmedtje, Jr, MD Denisse Diaz, MD and Vivian Fonseca, MD)
The purpose of this review is to discuss the potential mechanisms unifying the pathogenesis of atherogenic factors in diabetes with toxic metal exposure, and the potential role of metal chelation.
Antihyperglycemic and Blood Pressure Effects of Empagliflozin in African Americans with Type 2 Diabetes and Hypertension
Co-authored by Keith C. Ferdinand (Joseph L. Izzo, Jisoo Lee, Leslie Meng, Jyothis George, Afshin Salsali, and Leo Seman)
Empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor indicated for type 2 diabetes (T2D), can lower blood pressure (BP) and reduce cardiovascular mortality in patients with T2D and pre-existing cardiovascular disease. Its effects in African Americans have been understudied.
Upcoming Events
ACCOuNT Pilot Grant Application
The African American Pharmacogenomic Consortium Network Transdisciplinary Collaborative Center (ACCOuNT TCC) – a partnership between ITM investigators and Northwestern University – is offering a Pilot Grant Program to stimulate community stakeholders to be the principal drivers of pharmacogenomics-enabling research projects that they conceive, plan, and execute with support from research collaborators.
Two projects focused on African American cardiovascular pharmacogenomics, or how a person’s genes impact their reaction to drugs for the heart and blood vessels, will be awarded each year. Awards will be made for up to $25,000 for each project. The applications must be submitted by April 26, 2019 at 5:00pm.

In addition to community-based organizations and clinician investigators, the organization is encouraging voluntary health organizations and public health departments to apply for funding. For more information please visit the link below.

Summer Training For Underrepresented Junior Facilty
Washington University in St. Louis School of Medicine offers an all-expense paid summer institute program, initiated and funded by the NHLBI, to increase diversity in the field of Cardiovascular Disease Comorbidities, Genetics and Epidemiology.
Program Includes:
Two consecutive summers with two-week all-expense paid
summer institute, Mid-Year & Annual Meeting to:

  • Establish partnerships between Mentors and Mentees based on mutualresearch interests

  • Participate in training via lectures and workshops on various topics relatedto Cardiovascular Disease Comorbidities, Genetics, and Epidemiology

  • Participate in special grant-writing sessions conducted by NHLBI scientificprogram staff and PRIDE faculty

  • Compete for Small Research Project (SRP) funding for generatingpreliminary data for subsequent NHLBI grant applications

  • Develop the skills needed to apply for research grants and promoting asustainable independent research program for career development
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