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May 23, 2019
News From Medscape
The following recommended articles on Medscape.com are freely available through the partnership between ABC and Medscape, no registration or login required.
'Conscience Law' For Health Care Providers Worries Some, Pleases Others
Critics contend the new “Protecting Statutory Conscience Rights in Health Care” rule could create more barriers to medical services for minority populations, while many religious health workers believe it’s an important step.
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AHA Abx Prophylaxis Guidelines Hit Moderate-Risk Target
The 2007 American Heart Association (AHA) guideline revision is reducing antibiotic prophylaxis among patients at moderate risk for infective endocarditis (IE), as intended, but is not driving the recent surge in hospitalizations for these life-threatening infections, according to a Canadian analysis.
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EXTEND Published: tPA Success Up to 9 Hours After Stroke
The results of the EXTEND trial show that more patients presenting between 4.5 and 9 hours treated with tPA (alteplase) under these conditions achieved a score of 0 or 1 on the modified Rankin scale (indicating no deficits or minimal deficits, respectively) than those give placebo.
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Kaiser Launches Online Network to Address Patients' Social Needs
Kaiser Permanente, the national health maintenance organization (HMO) and integrated delivery system based in Oakland, California, is launching a "social health network" designed to connect its providers online with community services that can help patients with unmet social and economic needs.
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Items of Interest
Novel Technique Reduces Obstruction Risk in Heart Valve Replacement
Researchers at the National, Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, have developed a novel technique that prevents the obstruction of blood flow, a common fatal complication of transcatheter mitral valve replacement (TMVR).
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Urban Studies Institute Receives $250,000 Grant to Study Mobility Challenges, Improve Health Outcomes
Georgia State University’s Urban Studies Institute has been awarded a two-year, $250,000 grant under Systems for Action, a national program of the Robert Wood Johnson Foundation, to study the mobility challenges limiting low-income, chronically ill patients in accessing healthcare, healthy food and other activities that enhance physical and mental well-being.
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Recent Guidelines & Scientific Statements
AHA/ASA Back Four-Tier System for Stroke Care
A four-tier system of hospitals was endorsed by the American Heart Association (AHA)/American Stroke Association (ASA) in an updated policy statement on the organization of acute stroke care in the U.S.
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ACOG Releases Comprehensive Guidance on How to Treat the Leading Cause of U.S. Maternal Deaths: Heart Disease in Pregnancy
The American College of Obstetricians and Gynecologists (ACOG) released comprehensive guidance on pregnancy and heart disease. In the United States, cardiovascular disease (CVD) is now the leading cause of death in pregnancy and the postpartum period. It constitutes 26.5% of pregnancy-related deaths, with higher rates of mortality among women of color and women with lower incomes.
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SCAI Releases New Consensus Document on Classification Stages of Cardiogenic Shock
A newly released expert consensus statement proposes a classification schema for cardiogenic shock (CS) that will facilitate communication in both the clinical and research settings.
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Use of Lipoprotein(a) in Clinical Practice: A Biomarker Whose Time Has Come; A Scientific Statement From the National Lipid Association
Observational and genetic evidence strongly support a causal relationship between high plasma concentrations of Lp(a) and increased risk of atherosclerotic cardiovascular disease–related events, such as myocardial infarction and stroke, and valvular aortic stenosis. In this scientific statement, we review an array of evidence-based considerations for testing of Lp(a) in clinical practice and the utilization of Lp(a) levels to inform treatment strategies in primary and secondary prevention
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Enhancing the Value of PCSK9 Monoclonal Antibodies by Identifying Patients Most Likely to Benefit
This NLA Statement provides updated guidance to the clinician for enhancing the value of alirocumab and evolocumab in clinical practice based on the most updated costs of these agents.
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Featured Articles by Members
ABC Members: We welcome your published research submissions and articles for inclusion in future issues of Clinical Updates and Insights. Email Rachel Williams at rwilliams@abcardio.org and please attach file or include links to the original published work and/or abstract.
The Association of Black Cardiologists (ABC) Cardiovascular Implementation Study (CVIS): A Research Registry Integrating Social Determinants to Support Care for Underserved Patients
Co-authored by Elizabeth O. Ofili, Barbara Hutchinson, Felix Sogade, Icilma Fergus, Phillip Duncan, Joe Hargrove, Andre Artis, Osita Onyekwere, Wayne Batchelor, Marcus Williams, Anekwe Onwuanyi, Henry Okafor, Priscilla Pemu, Kevin Thomas, David Smith, David Gbadebo, B. Waine Kong, Cassandra McCullough, et al.

The ABC Cardiovascular Implementation Study (CVIS) is a comprehensive prospective cohort registry that integrates social determinants of health. ABC CVIS uses real world clinical practice data to address critical gaps in care by facilitating robust participation of African Americans and other minorities in clinical trials.
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