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May 30, 2019
News From Medscape
The following recommended articles on are freely available through the partnership between ABC and Medscape, no registration or login required.
Large Quantities of Grapefruit Juice Prolong QT Interval
Drinking large quantities of grapefruit juice may prolong the QT interval, especially in women and those who already have long QT syndrome (LQTS), new research suggests.
Only 1 in 5 With High-Risk AF Leave ED on Anticoagulant
People with atrial fibrillation (AF) who underwent treatment and were discharged directly from one of three emergency departments (EDs) in South Florida were much less likely to receive a prescription for an oral anticoagulant compared to patients who were admitted for observation or for inpatient care, a new study shows.
Few Cardiologists Referring Patients for Palliative Care
Although heart disease is the leading cause of death in the United States, few patients with heart disease are referred to palliative care, and for those that do receive such a referral this occurs much too late, a new study shows.
For First Time, More Doctors Employed Than Self-Employed: AMA
For the first-time, the number of employed physicians outstrips the number who are self-employed, according to a new survey by the American Medical Association (AMA).
Items of Interest
Fertility Treatment Linked to Peripartum Cardiomyopathy
The risk of peripartum cardiomyopathy (PPCM) is up to five times higher in mothers who undergo common fertility treatments like intracytoplasmic sperm injection (ICM) and in vitro fertilization (IVF), according to data presented at Heart Failure 2019 in Athens.
Expert Consensus Published on Use of Imaging to Guide Heart Attack Treatment
Imaging provides a more precise diagnosis of a heart attack that can be used to individualize treatment. That's the main message of an expert consensus paper published today in European Heart Journal, a journal of the European Society of Cardiology (ESC), and presented at EuroPCR in Paris, France.
E-cigarette Flavors Found to be Toxic
Recent research published in the journal Frontiers in Physiology examines the effect of electronic cigarette vapors on two types of white blood cell. The findings suggest that the compounds that give e-cigarettes their flavor are toxic, with some flavors being worse than others.
FDA Grants Priority Review for Vascepa sNDA
Amarin Corp. plc announced that its supplemental new drug application (sNDA) for Vascepa (icosapent ethyl) capsules has been accepted for filing and granted Priority Review designation by the U.S. Food and Drug Administration (FDA).
Heart Attack Victims Wait an Average of 3 Hours to Get Help — Here's Why
Researchers have identified a new barrier to timely care for MI patients; a perceived inability to act that leaves them immobilized and unable to seek professional help, in some cases for an excess of 24 hours.
Featured Articles by Members
ABC Members: We welcome your published research submissions and articles for inclusion in future issues of Clinical Updates and Insights. Email Rachel Williams at and please attach file or include links to the original published work and/or abstract.
Premature Battery Depletion Due To Compromised Low-Voltage Capacitor in a Family of Defibrillators
Co-authored by Walter K. Clair, MD, MPH (with Jay A. Montgomery, MD, Janice Y. Sensing, ARNP, Sandra D. Saunders, ARNP, Robert L. Abraham, MD, Arvindh N. Kanagasundram, MD, Christopher R. Ellis, MD, George H. Crossley III, MD, et al.)
Undetected premature battery depletion in this population of ICDs has the potential to expose a patient to an interval of time where the device is unable to provide therapy. However, with enrollment in remote monitoring, regular follow‐up, and attention to audible alerts, the risk of therapy loss due to low‐voltage state can be effectively mitigated.
Effect of Transcatheter Aortic Valve Implantation on Renal Function in Patients With Previous Renal Dysfunction
Co-authored by Alexis K. Okoh, MD and Setri Fugar, MD (with Kamrani Kambiz, MD, Dileep Unnikrishnan, MD, Christoph Sossou, MD, Mohammed Thawabi, MD, Amer Hawatmeh, MD, Bruce Haik, MD, Chunguang Chen, MD, Marc Cohen, MD, Mark J. Russo, MD, MS)
The study aims to investigate the incidence of immediate renal function improvement in renal dysfunction patients who had transcatheter aortic valve implantation (TAVI). TAVI patients with ≥ moderate reduced renal function [estimated GFR ≤ 60 ml/min/1.73 m2] at baseline were identified from a prospectively maintained database.
Improved Pathways To Hypertension Control And Elimination of Disparities: Are We There Yet?
Co-authored by Keith C. Ferdinand, MD (and Carola Maraboto, MD)
Hypertension, globally the most prevalent and potent CVD risk factor, is disproportionately uncontrolled in US minorities, including not only Blacks, but also Hispanics and Asian Americans. Although reasons for this disturbing lag in CVD progress are unclear and probably multifactorial, the obesity epidemic and co‐morbid hypertension are troubling.
Application of Community-Engaged Research to Inform the Development and Implementation of a Peer-Delivered Mobile Health Intervention for Adults With Serious Mental Illness
Co-authored by LaPrincess Brewer, MD (with Karen Fortuna, PhD; Paul Barr, PhD; Carly Goldstein, PhD; Robert Walker, MS, COAPS; Alexandra Zagaria, BA; Stephen Bartels, MD, MS)
The aim of this study was to present a framework that can be used as a guide for researchers and certified peer specialists to develop and implement peer-delivered mHealth interventions in community settings.
Cardiovascular Disease and Mortality in Adults Aged 60 Years and Up According to Recommendations by the American College of Cardiology/American Heart Association and American College of Physicians/American Academy of Family Physicians
Co-authored by D. Edmund Anstey and Gbenga Ogedegbe (with Byron C. Jaeger, Adam P. Bress, John N. Booth III, Mark Butler, Donald Clark III, George Howard, Jolaade Kalinowski, D. Leann Long, Timothy B. Plante, Daichi Shimbo, Mario Sims, et al.)
Adults recommended initiation or intensification of antihypertensive medication by the ACC/AHA but not the ACP/AAFP guideline have high atherosclerotic cardiovascular disease risk that may be reduced through treatment initiation or intensification.
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