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Antibody shrinks tumors of 7 cancers
Medical News Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A single antibody caused tumors from seven different human cancers transplanted into mice to shrink or disappear, according to a new study led by Stanford University School of Medicine in the U.S. The researchers hope to repeat this dramatic finding with tests in humans within the next two years. More

Genetic risk, stressful early infancy increase risk for schizophrenia
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Working with genetically engineered mice and the genomes of thousands of people with schizophrenia, researchers at Johns Hopkins say they now better understand how both nature and nurture can affect one's risks for schizophrenia and abnormal brain development in general. More

Gene patent ruling sent back to lower court
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Supreme Court has set aside a ruling that Myriad Genetics could patent two genes linked to breast and ovarian cancers, and ordered further review by a lower court. The Myriad case has been closely watched by the biotechnology industry, with some insiders suggesting a ruling against patenting could have a devastating effect on future innovation — including the fledgling field of personalized medicine. More

 Biotech/Diagnostics/Personalized Medicine

Study: Pregnancy ups risk of heart attack
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pregnancy and hormonal changes that continue 12 weeks after giving birth increase a woman's risk of heart attack, researchers said. Although the likelihood of having a heart attack during pregnancy is very low — just 1 in every 16,000 deliveries — it is still 3 to 4 times higher than non-pregnant women of the same age. More

Colorectal cancer app now available for patients
The Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The College of American Pathologists has partnered with CollabRx to provide patients with late-stage colon cancer access to cutting-edge information that could change their lives. Patients now can access the recently released Therapy Finder — Colorectal Cancer application through the College's website and patient portal,, to find personalized information on cancer therapies. More

Introducing mySentry™ from Medtronic...

The world’s first remote glucose monitor designed to provide protection from overnight hypoglycemia. MORE
Our activities touch many lives
AstraZeneca is a global, innovation-driven, integrated biopharmaceutical company. We discover, develop, manufacture and market prescription medicines for cancer, cardiovascular, gastrointestinal and infection. MORE

 Regenerative Medicine

Gene therapy shows promise against sickle cell
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have developed a gene therapy strategy that feasibly could treat both beta-thalassemia and sickle cell disease. The technology is based on delivery of a lentiviral vector carrying both the human beta-globin gene and an ankyrin insulator to improve gene transcripton and translation, and boost levels of beta-globin production. The Weill Cornell Medical College-led team that reports on the development has in parallel devised a simple assay to predict how well individual patients are likely to respond to the treatment. More

Study shows stem cell's potential for heart treatment
Houston Chronicle    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Houston researchers are reporting adult stem cells have a modest benefit in younger patients with heart failure, the first large-scale evidence that the controversial yet promising new therapy can be developed to help millions of people with the disease. A clinical trial showed cells derived from patients' own bone marrow produce a small but significant increase in the heart's ability to pump oxygen-rich blood. More

 Emerging Medical Technologies

FDA spells out new guidelines for medical device makers
MedCity News via WRAL Tech Wire    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The U.S. Food and Drug Administration issued new guidelines March 27 to help device makers understand how FDA reviewers evaluate premarket approval for high-risk devices and de novo submissions for moderate risk devices. In doing so, the agency reiterated a desire to provide clarity, consistency and transparency to a process that device manufacturers often have charged as unpredictable, capricious and confusing. More

Cell printing technology holds promise for tissue engineering
PRLog    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A novel method for printing human cells onto surfaces in defined patterns can help advance research on tissue engineering and regeneration, as described in an article in "Tissue Engineering," a journal from Mary Ann Liebert Inc. More

FDA panel urges review of stent
The Wall Street Journal    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A federal advisory panel has decided there isn't enough evidence to support keeping Stryker's Wingspan stent on the market, raising the possibility the Food and Drug Administration might withdraw its approval of the stroke-treatment product. The device is used in fewer than 2,000 patients a year who have had multiple strokes from intracranial-artery blockage. More

 Managed Healthcare News

Some insurers paying patients who agree to cheaper care
Kaiser Health News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In recent years, insurers have tried to cajole consumers into using less-expensive healthcare providers by promising lower co-payments and other cost-sharing breaks for members who select those doctors and hospitals. Lately, they're trying an even more direct approach: cash rewards. More

California seeks limits on small-business self-insurance trend
Los Angeles Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Sensing a fresh threat to state and federal healthcare reforms, California insurance officials are seeking new limits on a controversial form of health coverage insurers are selling to small employers. At issue is a new type of self-insurance for small businesses with as few as 25 workers. More

 FDA: New Treatments and Technology

Pharma scales back drug samples to physican offices
American Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pharmaceutical companies have slashed their sales rep force by about 30 percent from a high of 105,000 five years ago, according to industry figures. And as the number of detailers has fallen, so, too, has another hallmark of pharmaceutical marketing: drug samples. Drugmaker spending on the samples that drug reps leave behind in physician offices has gone down by 25 percent since 2007, a global pharmaceutical market-research firm said. More

FDA working to trim hospital 'alarm fatigue'
The Boston Globe    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Food and Drug Administration is taking steps to reduce "alarm fatigue" in hospitals by intensifying its pre-market review of medical devices that sound alarms and could contribute to the desensitization of nurses — a problem that The Boston Globe reported in 2011 was linked to hundreds of deaths. More

"Sickle cell disease occurs more often among people from parts of the world where malaria is or was common. It is believed that people who carry the sickle cell trait are less likely to have severe forms of malaria, according to the Centers for Disease Control and Prevention."
Genomics Biotech and Emerging Medical Technologies Institute eBrief
Colby Horton, Vice President of Publishing, 469.420.2601
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Christine Kraly, Content Editor, 469.420.2685   
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