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.FITNESS & WELLNESS
20 cardio exercises to do at home with minimal equipment, from beginner to advanced
Medical News Today
People do not need a lot of equipment for cardiovascular exercise. Instead, they can take part in cardio training at home by working their own body weight.
The American College of Sports Medicine recommend people engage in 150–300 minutes of moderate physical activity a week.
The following exercises allow a person to perform cardio almost anywhere, such as in their home, public park or outdoor space.
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Afternoon vs. morning exercise offers greater benefit for men at high metabolic risk
Healio
Men with excess weight or type 2 diabetes may reap more pronounced metabolic benefits from exercise when training is performed in the afternoon vs. morning, according to findings from a small, retrospective study.
“Exercise is the cornerstone for the prevention and treatment of metabolic diseases like diabetes,” Patrick Schrauwen, PhD, professor of metabolic aspects of type 2 diabetes in the nutrition and movement sciences department at Maastricht University in the Netherlands, told Healio.
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What are the mental and physical health benefits of exercise?
Medical News Today
Exercise benefits both mental health and physical health. Indeed, the National Institute on Aging say studies show that “taking it easy” is risky.
The Centers for Disease Control and Prevention say that “Regular physical activity is one of the most important things you can do for your health,” and everyone can benefit.
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.DIET & NUTRITION
Chicken diet: Is it healthy to eat only chicken?
Healthline
The chicken diet is a simple way of eating that involves eating only chicken for each meal throughout the day.
Proponents of the diet claim it can promote rapid fat loss with a minimal focus on meal planning, in theory helping people stick to the diet.
That said, most health professionals warn against such diets, as they eliminate major food groups, leaving you at risk of nutrient deficiencies.
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What you need to know about the raw vegan diet
Shape
For those who love eating but absolutely despise cooking, the idea of never having to attempt to grill a steak to perfection or stand over a piping hot stove for an hour sounds like a dream. And with the raw vegan diet — which involves kicking your typical cooking techniques to the curb and filling up on uncooked items such as fresh, raw produce, nuts, seeds and beans — that fantasy can be a reality.
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New US dietary guidelines expand nutrient considerations for life stages
Regulatory Focus
The U.S. Department of Agriculture and Department of Health and Human Services have jointly published the Dietary Guidelines for Americans every 5 years since 1980 to provide science-based dietary recommendations to promote health and prevent chronic disease. The guidelines inform federal food and nutrition policy programs as well as local, state and national health promotion and disease prevention initiatives. In addition, professionals in public health, healthcare, education and other sectors use the guidelines to educate the public about diet and health.
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.RESEARCH & DEVELOPMENT
Is stretching better than walking for reducing blood pressure?
Medical News Today
For anyone who has had to spend more time at home as a result of the coronavirus pandemic, news that simple stretching exercises can help reduce blood pressure may come as a pleasant surprise.
“When you’re relaxing in the evening, instead of just sitting on the couch, you can get down on the floor and stretch while you’re watching TV,” says Dr. Phil Chilibeck, Ph.D., professor of kinesiology at the University of Saskatchewan in Saskatoon, Canada, and co-author of the new study.
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Plant-based or keto diet? Novel study yields surprising results
Medscape
For appetite control, a low-fat, plant-based diet has advantages over a low-carbohydrate, animal-based ketogenic diet, although the keto diet wins when it comes to keeping post-meal glucose and insulin levels in check, new research suggests.
In a highly controlled crossover study conducted at the National Institutes of Health, people consumed fewer daily calories when on a low-fat, plant-based diet, but their insulin and blood glucose levels were higher than when they followed a low-carbohydrate, animal-based diet.
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Researchers discover exercise can counteract the toll of chronic inflammation
Inverse
Inflammation is a vital, sometimes life-saving, feature of the immune system. It's one of the first steps of the body's healing process, helping remove or repair harmful stimuli.
But when inflammation lingers for months or years, it can cause devastating damage — wasting away muscles and contributing to chronic inflammatory diseases including stroke, chronic respiratory diseases and cancer.
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.VITAMINS & PHARMACEUTICALS
How vitamins, steroids and potential antivirals might affect SARS-CoV-2
AAAS via EurekAlert!
Evidence is emerging that vitamin D - and possibly vitamins K and A - might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they - and other antiviral drugs - might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so might reduce SARS-CoV-2 infectivity.
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Migraine vitamins: Do they work?
Medical News Today
Migraine episodes can be debilitating. While many people find relief from taking prescription medications, there is limited evidence that certain vitamins may reduce the severity, duration or frequency of migraine.
Researchers have looked at the impact numerous nutrients have on migraine, with some of the most studied including vitamin B2, magnesium and coenzyme Q10.
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7 scientific health benefits of vitamin C
Everyday Health
Vitamin C is one of the most talked about vitamins. The nutrient gets special buzz for its immune-boosting potential. But touting vitamin C's ability to shorten the common cold only scratches the surface of its role in the body.
This antioxidant isn’t naturally made by the body, so it’s crucial to obtain it from vitamin C–rich foods, according to the Mayo Clinic.
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.NAMCP UPDATES
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| Home Instead, the leading provider of in-home care for older adults, has launched a new brand identity and campaign to promote the evolving organization. Formerly known as Home Instead Senior Care, the company was founded in 1994 by Paul and Lori Hogan to address a need for personalized care to allow adults to age at home, inspired by Paul’s own grandmother. It has since grown to more than 1,200 independently owned and operated franchises across the globe, which employ 90,000 professional caregivers and deliver more than 80 million hours of care annually. Created in partnership with creative agency Energy BBDO, the brand’s update includes a simplified logo and the removal of the term “senior care” from the official name – Home Instead. The changes are meant to be more inclusive and a reflection of the evolving global language around the way people talk about older adults. The name change also allows the brand to more broadly address helping aging adults meet their needs wherever they are on their care journey. Please click here to view the full press release.
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| Verrica Pharmaceuticals Inc., a dermatology therapeutics company developing medications for skin diseases requiring medical interventions, today announced that it has resubmitted the New Drug Application (NDA) for VP-102 for the treatment of molluscum contagiosum (molluscum) to the U.S. Food and Drug Administration (FDA). The NDA for VP-102 was resubmitted based on the outcome and final minutes of a Type A meeting with the FDA, which was conducted to obtain clarity on the Complete Response Letter (CRL) issued by the FDA in July 2020. Click here to view the full press release.
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| Biodesix, Inc., a leading data-driven diagnostic solutions company with a focus in lung disease, today announced publication of an analysis of the company’s Nodify XL2® lung nodule test. The test supports clinical decision-making for suspicious nodules by more accurately identifying patients with a very low risk of malignancy and shifting those patients into surveillance, thereby minimizing invasive procedures on those with benign nodules. Please click here to view the full press release.
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| LivaNova PLC, a market-leading medical technology and innovation company, today announced the publication of a new study in the International Journal of Bipolar Disorders that showed adding Vagus Nerve Stimulation Therapy (VNS Therapy®) to treatment as usual (TAU) significantly improves outcomes in patients with treatment-resistant bipolar depression (TRBD). The study examined patients from a five-year prospective registry and found 63% of TRBD patients treated with adjunctive VNS Therapy in addition to TAU had a significant reduction in depressive symptoms, as measured by a 50% or greater reduction in the Montgomery–Åsberg Depression Rating Scale (MADRS), compared with 39% of patients in the TAU alone group. Click here to view the entire press release. Click here to view the entire press release.
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| Additionally, LivaNova PLC announced a publication in Contemporary Clinical Trials, which details the design for “A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression” or the RECOVER clinical study. RECOVER is currently under way as part of a Coverage with Evidence Development framework of the U.S. Centers for Medicare & Medicaid Services’ (CMS) National Coverage Determination process. Click here to view the entire press release.
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| In late 2018, the National Association of Managed Care Physicians (NAMCP) decided to create the Value Based Care Council (VBCC). The VBCC mission supports empowering medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. The goal is to improve the integration of cost, quality, and access in the clinical decision making process so as to enhance the effectiveness and efficiency of extracting value from the associated spend in order to optimize outcomes.
Pursuant to the above, and in response to an unmet need in the marketplace, the VBCC developed a short form in order to enhance the effectiveness and efficiency with which value propositions can be shared between industry and the medical leadership of various payers throughout the country. This same short form provides a concise and consistent manner with which value propositions can be shared and provides the ability to align expectations prior to actually conducting conversations or having a meeting regarding a product or service.
The Product Value Proposition Customer Engagement Short Form can be found on the NAMCP website (www.namcp.org) in the Value Based Care Council subsection of the Councils tab, under tools and resources. Please contact Will Williams at wwilliams@namcp.org with questions or for additional information.
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| Jazz Pharmaceuticals is excited to announce the approval of ZEPZELCA™ (lurbinectedin) for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. ZEPZELCA is a second-line therapy that has been studied in both platinum-sensitive and -resistant SCLC patients. Please click here for more information.
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| Takeda Pharmaceuticals is part of, "The Fight Is In Us", an initiative to maximize the individual and societal benefit of COVID-19 plasma. The campaign will focus on recruiting COVID-19 survivors to donate their plasma at licensed blood and plasma donor centers.- If you’ve recovered from #COVID19, your immune system has antibodies that could be used as a treatment. See if you can help others by donating plasma www.TheFightIsInUs.org. #TheFightIsInUS
- The antibodies that helped you or someone you know fight off COVID-19 may be able to help others. Visit www.TheFightIsInUs.org to see if you qualify to donate plasma. #TheFightIsInUs
You are a survivor, now you could be a hero. Plasma from recovered #COVID19 patients could play a key role in creating a potential therapy for coronavirus. Learn how you can donate at www.TheFightIsInUs.org #TheFightIsInUs
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| Biodesix, Inc., a leading diagnostic company in lung disease, recently announced a partnership with Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) to bring a COVID-19 Droplet Digital PCR (ddPCR) test to the FDA for an Emergency Use Authorization (EUA) approval to support the escalating need for testing in the U.S. Two studies published this month, ahead of peer review, reported that ddPCR testing showed superior sensitivity and precision for clinical detection of SARS-CoV-2 (the virus that causes COVID-19) compared to existing test methods that are performed using qPCR. Biodesix currently has a focus on lung disease and offers other diagnostic testing for lung cancer utilizing the ddPCR platform.Click here for more information.
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| "Modeling Cost-Effectiveness of On-Demand Treatment for Hereditary Angioedema Attack" was recently published in the Journal of Managed Care Pharmacy's February 2020 issue. Hereditary angioedema (HAE) is a rare disease that causes painful and potentially fatal episodes of swelling (attacks). HAE attacks can be unpredictable and the need to treat sudden attacks promptly and effectively is critical to minimize risk of hospitalization, morbidity, and mortality. A cost-effectiveness model was evaluated that considers evaluation of on-demand medications, healthcare utilization and patient well-being. For access to the publication, please click here.
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| Biodesix, Inc. announced initiation of the next phase of their biomarker development program with Merck KGaA, Darmstadt, Germany and Pfizer Inc. The companies have completed initial discovery and development of a new proteomic test that identifies likely responders to the anti-PD-L1 checkpoint inhibitor (BAVENCIO®) (avelumab). Development efforts will now focus on transferring the test into Biodesix's CLIA lab in Boulder, CO for clinical phase test validation. The new test was developed through retrospective analysis of the circulating proteome of cancer patients treated with the investigational drug candidate, utilizing the proprietary Biodesix Diagnostic Cortex™ artificial intelligence (AI) platform. Click here to read the full press release.
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| The NAMCP Medical Directors Institute recently held the first meeting of its Executive Leadership Council (ELC) at the recent Fall Managed Care Forum. The NAMCP Medical Directors Institute decided in late 2018 to create the Value Based Care Council (VBCC) with a mission to empower medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. Click here to view an overview of the genesis, formation, and work of NAMCP's Value Based Care Council. Please click here to view the press release.
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| LivaNova PLC (NASDAQ:LIVN), a market-leading medical technology and innovation company, today announced the first patient enrolled in "A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression" (RECOVER). The study will evaluate Vagus Nerve Stimulation Therapy (VNS Therapy) for Treatment-Resistant Depression (TRD) in accordance with the U.S. Centers for Medicare & Medicaid Services (CMS) National Coverage Determination as part of its Coverage with Evidence Development Program. The first patient was enrolled by Dr. Azfar Malik in St. Louis. Click here to read the full press release.
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| Biodesix, Inc. this week highlighted findings from multiple studies demonstrating the significance and clinical utility of its VeriStrat® blood-based proteomic test as a predictive biomarker for patient survival outcomes and as a diagnostic tool to improve the clinical management of patients with non-small cell lung cancer (NSCLC). This information is vital to implementing optimal treatment strategies for patients and supports disease state monitoring. To date, VeriStrat testing has helped more than 50,000 patients in determining the best treatment for their lung cancer. Click here to see the full press release. | |
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