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.FITNESS & WELLNESS
Exercise can bolster your brainpower at the office
Bloomberg
Got a big day at work? Exercise can strengthen your brainpower and bolster your emotional fortitude, says Panteleimon Ekkekakis, a professor of exercise psychology at Iowa State University, who studies how working out affects the mind and mood.
Although any type of exercise can improve health, cardio triggers optimal cognitive and emotional states, Ekkekakis says.
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Exercise during pregnancy may help mitigate negative effects of parental obesity in children
News-Medical.Net
New research in mice suggests that exercising during pregnancy may help prevent children-;especially boys-;from developing health problems related to their parents' obesity. The study is published ahead of print in the Journal of Applied Physiology.
Obesity during pregnancy increases the risk that the children of obese parents will have metabolic disorders, such as diabetes, later in life.
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Face yoga for inner and outer radiance?
Healthline
In the ongoing quest to age gracefully and exude a sense of inner peace, many people are searching for natural, affordable options that will help them look and feel better.
Face yoga involves massage and exercises that stimulate the muscles, skin and lymphatic system. This technique is designed to soften and relax your face muscles to help alleviate tension, stress and worry. This may also help you stop making the facial expressions associated with those feelings.
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.DIET & NUTRITION
The low residue diet
U.S. News & World Report
You wont' hear this advice often: Leave fiber out of your diet. It’s the opposite of all dietary recommendations for good health. It’s also a strategy for sensitive guts called the low residue diet. “The purpose of the low residue diet is to reduce roughage that generates cramps, gas and other symptoms,” says Dr. Wilson Jackson, a gastroenterologist based in Harrisburg, Pennsylvania.
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Mediterranean diet may have benefits for cognitive functioning in later life
News-Medical.Net
People who eat a Mediterranean-style diet--particularly one rich in green leafy vegetables and low in meat--are more likely to stay mentally sharp in later life, a study shows.
Closely adhering to a Mediterranean diet was associated with higher scores on a range of memory and thinking tests among adults in their late 70s, the research found.
The study found no link, however, between the Mediterranean-style diet and better brain health.
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Heart-healthy foods: What to eat and what to avoid
Medical News Today
Eating foods for a healthy heart involves keeping to a nutrient-rich diet. Primary sources are plant-based foods, including fruits, vegetables, nuts, whole grains and beans. Moderate amounts of dairy and fish are beneficial as well.
A diet that can help prevent or manage heart failure also excludes certain foods. Experts recommend limiting the intake of salty foods and those that are high in saturated fat, such as sausage and fatty cuts of red meat.
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.RESEARCH & DEVELOPMENT
Resistance exercise after bariatric surgery prevents bone loss
Endocrinology Advisor
Participation in a guided exercise program has demonstrated improvements in bone mineral density in patients who undergo bariatric surgery, according to research published in the Journal of Bone and Mineral Research.
Patients who undergo bariatric surgery have an increased risk of fracture compared to obese patients who do not have the surgery.
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Black coffee can be good for your heart, studies show
CNN
It's another home run for coffee consumption — as long as it's black and caffeinated, that is.
Drinking one or more cups of plain, leaded coffee a day was associated with a long-term reduced risk of heart failure, according to a review of diet data from three major studies using analytic tools from the American Heart Association.
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Even low-intensity exercise can help during cancer treatments
HealthDay
If you have cancer and you're trying to exercise to boost your health, new research suggests you don't have to knock yourself out during your workout.
Light exercise is just as beneficial as more demanding workouts for cancer patients, the researchers found.
Previous research has shown that physical activity can improve cancer patients' physical and mental health, reduce fatigue and ease the side effects of treatment.
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.VITAMINS & PHARMACEUTICALS
Vitamin C, zinc don't lessen COVID-19 symptoms, study finds
CNN
Can vitamin C and zinc help you fight off COVID-19?
No, not even at high doses, according to the first randomized clinical trial to test the two supplements under medical supervision.
Despite the popular use of vitamin C and zinc to fight off or lessen the severity of viral colds and flu, the new study, published in JAMA Network Open, found the two supplements were of no benefit to people isolating at home with COVID-19.
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Are gummy vitamins as good as traditional food supplements?
Big Easy Magazine
Have you ever faced a problem deciding whether you should go for a traditional food supplement or the yummy gummy vitamins such as Gummies Garden? If you want some help in making this decision, let us help you find out the answer to the question, Are gummy vitamins as good as traditional food supplements?
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Vitamin D supplementation: Possible gain in life years combined with cost savings
German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) via ScienceDaily
Scientists have now calculated: If all Germans over the age of 50 were to take vitamin D supplements, up to 30,000 cancer deaths per year could possibly be avoided and more than 300,000 years of life could be gained — in addition, health care costs could be saved.
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.NAMCP UPDATES
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| Home Instead, the leading provider of in-home care for older adults, has launched a new brand identity and campaign to promote the evolving organization. Formerly known as Home Instead Senior Care, the company was founded in 1994 by Paul and Lori Hogan to address a need for personalized care to allow adults to age at home, inspired by Paul’s own grandmother. It has since grown to more than 1,200 independently owned and operated franchises across the globe, which employ 90,000 professional caregivers and deliver more than 80 million hours of care annually. Created in partnership with creative agency Energy BBDO, the brand’s update includes a simplified logo and the removal of the term “senior care” from the official name – Home Instead. The changes are meant to be more inclusive and a reflection of the evolving global language around the way people talk about older adults. The name change also allows the brand to more broadly address helping aging adults meet their needs wherever they are on their care journey. Please click here to view the full press release.
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| Verrica Pharmaceuticals Inc., a dermatology therapeutics company developing medications for skin diseases requiring medical interventions, today announced that it has resubmitted the New Drug Application (NDA) for VP-102 for the treatment of molluscum contagiosum (molluscum) to the U.S. Food and Drug Administration (FDA). The NDA for VP-102 was resubmitted based on the outcome and final minutes of a Type A meeting with the FDA, which was conducted to obtain clarity on the Complete Response Letter (CRL) issued by the FDA in July 2020. Click here to view the full press release.
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| Biodesix, Inc., a leading data-driven diagnostic solutions company with a focus in lung disease, today announced publication of an analysis of the company’s Nodify XL2® lung nodule test. The test supports clinical decision-making for suspicious nodules by more accurately identifying patients with a very low risk of malignancy and shifting those patients into surveillance, thereby minimizing invasive procedures on those with benign nodules. Please click here to view the full press release.
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| LivaNova PLC, a market-leading medical technology and innovation company, today announced the publication of a new study in the International Journal of Bipolar Disorders that showed adding Vagus Nerve Stimulation Therapy (VNS Therapy®) to treatment as usual (TAU) significantly improves outcomes in patients with treatment-resistant bipolar depression (TRBD). The study examined patients from a five-year prospective registry and found 63% of TRBD patients treated with adjunctive VNS Therapy in addition to TAU had a significant reduction in depressive symptoms, as measured by a 50% or greater reduction in the Montgomery–Åsberg Depression Rating Scale (MADRS), compared with 39% of patients in the TAU alone group. Click here to view the entire press release. Click here to view the entire press release.
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| Additionally, LivaNova PLC announced a publication in Contemporary Clinical Trials, which details the design for “A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression” or the RECOVER clinical study. RECOVER is currently under way as part of a Coverage with Evidence Development framework of the U.S. Centers for Medicare & Medicaid Services’ (CMS) National Coverage Determination process. Click here to view the entire press release.
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| In late 2018, the National Association of Managed Care Physicians (NAMCP) decided to create the Value Based Care Council (VBCC). The VBCC mission supports empowering medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. The goal is to improve the integration of cost, quality, and access in the clinical decision making process so as to enhance the effectiveness and efficiency of extracting value from the associated spend in order to optimize outcomes.
Pursuant to the above, and in response to an unmet need in the marketplace, the VBCC developed a short form in order to enhance the effectiveness and efficiency with which value propositions can be shared between industry and the medical leadership of various payers throughout the country. This same short form provides a concise and consistent manner with which value propositions can be shared and provides the ability to align expectations prior to actually conducting conversations or having a meeting regarding a product or service.
The Product Value Proposition Customer Engagement Short Form can be found on the NAMCP website (www.namcp.org) in the Value Based Care Council subsection of the Councils tab, under tools and resources. Please contact Will Williams at wwilliams@namcp.org with questions or for additional information.
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| Jazz Pharmaceuticals is excited to announce the approval of ZEPZELCA™ (lurbinectedin) for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. ZEPZELCA is a second-line therapy that has been studied in both platinum-sensitive and -resistant SCLC patients. Please click here for more information.
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| Takeda Pharmaceuticals is part of, "The Fight Is In Us", an initiative to maximize the individual and societal benefit of COVID-19 plasma. The campaign will focus on recruiting COVID-19 survivors to donate their plasma at licensed blood and plasma donor centers.- If you’ve recovered from #COVID19, your immune system has antibodies that could be used as a treatment. See if you can help others by donating plasma www.TheFightIsInUs.org. #TheFightIsInUS
- The antibodies that helped you or someone you know fight off COVID-19 may be able to help others. Visit www.TheFightIsInUs.org to see if you qualify to donate plasma. #TheFightIsInUs
You are a survivor, now you could be a hero. Plasma from recovered #COVID19 patients could play a key role in creating a potential therapy for coronavirus. Learn how you can donate at www.TheFightIsInUs.org #TheFightIsInUs
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| Biodesix, Inc., a leading diagnostic company in lung disease, recently announced a partnership with Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) to bring a COVID-19 Droplet Digital PCR (ddPCR) test to the FDA for an Emergency Use Authorization (EUA) approval to support the escalating need for testing in the U.S. Two studies published this month, ahead of peer review, reported that ddPCR testing showed superior sensitivity and precision for clinical detection of SARS-CoV-2 (the virus that causes COVID-19) compared to existing test methods that are performed using qPCR. Biodesix currently has a focus on lung disease and offers other diagnostic testing for lung cancer utilizing the ddPCR platform.Click here for more information.
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| "Modeling Cost-Effectiveness of On-Demand Treatment for Hereditary Angioedema Attack" was recently published in the Journal of Managed Care Pharmacy's February 2020 issue. Hereditary angioedema (HAE) is a rare disease that causes painful and potentially fatal episodes of swelling (attacks). HAE attacks can be unpredictable and the need to treat sudden attacks promptly and effectively is critical to minimize risk of hospitalization, morbidity, and mortality. A cost-effectiveness model was evaluated that considers evaluation of on-demand medications, healthcare utilization and patient well-being. For access to the publication, please click here.
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| Biodesix, Inc. announced initiation of the next phase of their biomarker development program with Merck KGaA, Darmstadt, Germany and Pfizer Inc. The companies have completed initial discovery and development of a new proteomic test that identifies likely responders to the anti-PD-L1 checkpoint inhibitor (BAVENCIO®) (avelumab). Development efforts will now focus on transferring the test into Biodesix's CLIA lab in Boulder, CO for clinical phase test validation. The new test was developed through retrospective analysis of the circulating proteome of cancer patients treated with the investigational drug candidate, utilizing the proprietary Biodesix Diagnostic Cortex™ artificial intelligence (AI) platform. Click here to read the full press release.
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| The NAMCP Medical Directors Institute recently held the first meeting of its Executive Leadership Council (ELC) at the recent Fall Managed Care Forum. The NAMCP Medical Directors Institute decided in late 2018 to create the Value Based Care Council (VBCC) with a mission to empower medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. Click here to view an overview of the genesis, formation, and work of NAMCP's Value Based Care Council. Please click here to view the press release.
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| LivaNova PLC (NASDAQ:LIVN), a market-leading medical technology and innovation company, today announced the first patient enrolled in "A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression" (RECOVER). The study will evaluate Vagus Nerve Stimulation Therapy (VNS Therapy) for Treatment-Resistant Depression (TRD) in accordance with the U.S. Centers for Medicare & Medicaid Services (CMS) National Coverage Determination as part of its Coverage with Evidence Development Program. The first patient was enrolled by Dr. Azfar Malik in St. Louis. Click here to read the full press release.
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| Biodesix, Inc. this week highlighted findings from multiple studies demonstrating the significance and clinical utility of its VeriStrat® blood-based proteomic test as a predictive biomarker for patient survival outcomes and as a diagnostic tool to improve the clinical management of patients with non-small cell lung cancer (NSCLC). This information is vital to implementing optimal treatment strategies for patients and supports disease state monitoring. To date, VeriStrat testing has helped more than 50,000 patients in determining the best treatment for their lung cancer. Click here to see the full press release. | |
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