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Aug. 5, 2020
 
 
FITNESS & WELLNESS
 
 
Cardio fitness critical to exercise regimen
Reporter-Times
One of the main purposes of exercising is to improve muscle function and efficiency. One of the most important muscles in the body is your heart. Exercising one’s heart is usually done by what is referred to as cardiovascular exercise, or cardio for short. Cardiovascular exercise pushes your hearts ability to supply oxygen to working muscles over a long period of time.
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Here's how working out can make you more resilient to stress
Shape
When it comes to the physical health perks of exercise, you could probably rattle off a dozen benefits. But the mental health effects of working out are just as profound, making us happier, less stressed and more resilient, says Kelly McGonigal, Ph.D., author of The Joy of Movement. Here, she explains the incredibly powerful muscle-mind connection.
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Exercising safely after having a blood clot
U.S. News & World Report via WTOP News
Blood clots are nature’s way of helping stanch the flow of blood from a cut or wound. But blood can also clot while in the body — and that’s a danger. Deep vein thrombosis, or DVT, is the clinical name for this occurrence. When a blood clot, called a thrombus, forms in one or more of the deep veins in your body, usually in your legs, it can cause pain or swelling. It also can cause no noticeable symptoms.
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DIET & NUTRITION
 
 
How innovation and regulation have changed the nutrition industry
Manufacturing.net
According to recent research, the global personalized nutrition market was valued at $5.59 billion in 2018 and is expected to reach an astounding $11.35 billion by the year 2026. We continue to see an ever-increasing trend toward healthier foods, made from ingredients found in nature that protect the planet and its inhabitants.
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Matching meals to metabolism
Medscape
For many years, researchers and clinicians assumed that nutrition was a one-size-fits-all affair. Everybody needs the same nutrients from their food, they thought, and a vitamin pill or two could help dispense with any deficiencies.
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There’s more to nutrition than carbs and fat: Why micronutrients matter
The Great Courses Daily
When we’re trying to lose weight or be healthier, we often focus on the macronutrient content of our meals — the amount of carbohydrate, fat and protein. However, we should also consider the micronutrients, or the amount of smaller nutrients like vitamins and minerals that our food contains.
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RESEARCH & DEVELOPMENT
 
 
Studies show biology influences how we respond to exercise
Naples Florida Weekly
Getting enough physical activity can make both your body and mind feel better. It can also help prevent or delay health problems. Now, researchers are looking for ways to find out which exercises might best suit your body.
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Study: High dose fish oil supplement speeds exercise recovery
NutraIngredients
Daily supplementation with a high dose of fish oil can improve muscle recovery following a damaging bout of exercise, research has concluded. Current data suggests that fish oil supplementation likely enhances recovery and preserves strength following stressful exercise, with the positive influence mostly attributed to the anti-inflammatory and immunomodulatory properties conferred by EPA and DHA.
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Aerobic exercise may be key to unlocking improvement in metabolic associated fatty liver disease
Genetic Engineering & Biotechnology News
Metabolic associated fatty liver disease is the most prevalent chronic liver disease worldwide. It is recognized as the liver disease component of metabolic syndrome, which is mainly related to insulin resistance and genetic susceptibility.
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VITAMINS & PHARMACEUTICALS
 
 
Calcium, vitamin D deficiencies increase risk of osteoporosis
Pharmacy Times
A new study published in PLoS ONE has found that inadequate intake of calcium and vitamin D can significantly affect patients’ risk of osteoporosis. The study emphasized the population below the poverty line, for whom food insecurities can make vitamin and mineral intake even more challenging.
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What happens if you take too many vitamins?
Yahoo Life
When we think about vitamins, our main worries are usually focused on deficiency. We’re frequently warned about the dangers and symptoms associated with not getting enough of the nutrients we need to thrive and want to avoid getting sick. But what happens if you take too many vitamins?
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Do gummy vitamins actually do anything? Experts weigh in
Mic
Melissa Pandika writes: "Gummy vitamins are delicious. My parents take them, and when I sampled one out of curiosity on a recent trip home, I had to stop myself from popping 10 more. Apparently, I’m not the only one who finds them irresistible, as evidenced by the popularity of gummy vitamin brands like Olly, Hum and Hello Bello, with their bright, Insta-worthy packaging and chewy, fruit-snack like morsels."
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NAMCP UPDATES
 
 

In late 2018, the National Association of Managed Care Physicians (NAMCP) decided to create the Value Based Care Council (VBCC). The VBCC mission supports empowering medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. The goal is to improve the integration of cost, quality, and access in the clinical decision making process so as to enhance the effectiveness and efficiency of extracting value from the associated spend in order to optimize outcomes.

Pursuant to the above, and in response to an unmet need in the marketplace, the VBCC developed a short form in order to enhance the effectiveness and efficiency with which value propositions can be shared between industry and the medical leadership of various payers throughout the country. This same short form provides a concise and consistent manner with which value propositions can be shared and provides the ability to align expectations prior to actually conducting conversations or having a meeting regarding a product or service.

The Product Value Proposition Customer Engagement Short Form can be found on the NAMCP website (www.namcp.org) in the Value Based Care Council subsection of the Councils tab, under tools and resources. Please contact Will Williams at wwilliams@namcp.org with questions or for additional information.


Jazz Pharmaceuticals is excited to announce the approval of ZEPZELCA™ (lurbinectedin) for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. ZEPZELCA is a second-line therapy that has been studied in both platinum-sensitive and -resistant SCLC patients. Please click here for more information.


Takeda Pharmaceuticals is part of, "The Fight Is In Us", an initiative to maximize the individual and societal benefit of COVID-19 plasma. The campaign will focus on recruiting COVID-19 survivors to donate their plasma at licensed blood and plasma donor centers.
  • If you’ve recovered from #COVID19, your immune system has antibodies that could be used as a treatment. See if you can help others by donating plasma www.TheFightIsInUs.org. #TheFightIsInUS

  • The antibodies that helped you or someone you know fight off COVID-19 may be able to help others. Visit www.TheFightIsInUs.org to see if you qualify to donate plasma. #TheFightIsInUs
You are a survivor, now you could be a hero. Plasma from recovered #COVID19 patients could play a key role in creating a potential therapy for coronavirus. Learn how you can donate at www.TheFightIsInUs.org #TheFightIsInUs


Biodesix, Inc., a leading diagnostic company in lung disease, recently announced a partnership with Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) to bring a COVID-19 Droplet Digital PCR (ddPCR) test to the FDA for an Emergency Use Authorization (EUA) approval to support the escalating need for testing in the U.S. Two studies published this month, ahead of peer review, reported that ddPCR testing showed superior sensitivity and precision for clinical detection of SARS-CoV-2 (the virus that causes COVID-19) compared to existing test methods that are performed using qPCR. Biodesix currently has a focus on lung disease and offers other diagnostic testing for lung cancer utilizing the ddPCR platform.Click here for more information.


"Modeling Cost-Effectiveness of On-Demand Treatment for Hereditary Angioedema Attack" was recently published in the Journal of Managed Care Pharmacy's February 2020 issue. Hereditary angioedema (HAE) is a rare disease that causes painful and potentially fatal episodes of swelling (attacks). HAE attacks can be unpredictable and the need to treat sudden attacks promptly and effectively is critical to minimize risk of hospitalization, morbidity, and mortality. A cost-effectiveness model was evaluated that considers evaluation of on-demand medications, healthcare utilization and patient well-being. For access to the publication, please click here.


Biodesix, Inc. announced initiation of the next phase of their biomarker development program with Merck KGaA, Darmstadt, Germany and Pfizer Inc. The companies have completed initial discovery and development of a new proteomic test that identifies likely responders to the anti-PD-L1 checkpoint inhibitor (BAVENCIO®) (avelumab). Development efforts will now focus on transferring the test into Biodesix's CLIA lab in Boulder, CO for clinical phase test validation. The new test was developed through retrospective analysis of the circulating proteome of cancer patients treated with the investigational drug candidate, utilizing the proprietary Biodesix Diagnostic Cortex™ artificial intelligence (AI) platform. Click here to read the full press release.


The NAMCP Medical Directors Institute recently held the first meeting of its Executive Leadership Council (ELC) at the recent Fall Managed Care Forum. The NAMCP Medical Directors Institute decided in late 2018 to create the Value Based Care Council (VBCC) with a mission to empower medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. Click here to view an overview of the genesis, formation, and work of NAMCP's Value Based Care Council. Please click here to view the press release.


LivaNova PLC (NASDAQ:LIVN), a market-leading medical technology and innovation company, today announced the first patient enrolled in "A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression" (RECOVER). The study will evaluate Vagus Nerve Stimulation Therapy (VNS Therapy) for Treatment-Resistant Depression (TRD) in accordance with the U.S. Centers for Medicare & Medicaid Services (CMS) National Coverage Determination as part of its Coverage with Evidence Development Program. The first patient was enrolled by Dr. Azfar Malik in St. Louis. Click here to read the full press release.


Biodesix, Inc. this week highlighted findings from multiple studies demonstrating the significance and clinical utility of its VeriStrat® blood-based proteomic test as a predictive biomarker for patient survival outcomes and as a diagnostic tool to improve the clinical management of patients with non-small cell lung cancer (NSCLC). This information is vital to implementing optimal treatment strategies for patients and supports disease state monitoring. To date, VeriStrat testing has helped more than 50,000 patients in determining the best treatment for their lung cancer. Click here to see the full press release.
 
 
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Dennis Hall, Director of Publishing, 469-420-2656 | Download media kit
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