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Sept. 9, 2020
 
 
FITNESS & WELLNESS
 
 
Why recovery is the key to effective exercise: How to reboot your workout routine
CNN
Whether your exercise goals are for health, aesthetics or athletics, the means to those ends all come from changing your body composition. That's why our workouts focus on losing fat and building muscle. But true transformation in our bodies doesn't actually occur while we're training. It happens during recovery.
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Exercise on a vibration platform may provide short-term patellofemoral pain relief
Healio
A 4-week training protocol of hip, knee and core exercises on a full body, vibration platform may improve function and relieve pain in the short term for patients with patellofemoral pain syndrome, according to published results.
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Cardio isn’t enough. For a healthy heart, add resistance training.
The Washington Post
If the idea of exercising for cardiovascular health makes you think of spin class, it’s time to shift that thinking. In addition to traditional “cardio” regimens such as biking, running and high-intensity interval training, there is another kind of workout that benefits your heart: strength training.
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DIET & NUTRITION
 
 
Evening eating is associated with higher total calorie intake and lower diet quality
Medical Xpress
A study of nearly 1200 U.K. adults, being presented at this year's European and International Conference on Obesity, held online this year, suggests that there is a link between eating a larger proportion of one's daily energy intake during the evening, and having a higher total energy intake and lower quality of diet.
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Paleo vs. keto faceoff: Which of these ultra-popular diets is better for weight loss?
Parade
There are at least 100 types of different diets to choose from in 2020, but some are buzzier than others. Right now, you’re probably hearing a lot about the paleo and keto diets, which for some people have become more of a lifestyle than a short-term diet.
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Low carb diets often influenced by internet information and do not work for all: Study
Medical Xpress
Low carbohydrate diets are often driven by beliefs that are influenced by internet resources, and do not represent a one-size-fits all approach to dieting. In a new study led by the University of Glasgow and published today in Nature Scientific Reports, researchers have provided further insights into the motivations for following low carb diets and the experiences of current and past dieters.
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RESEARCH & DEVELOPMENT
 
 
Brain study reveals 1 type of exercise increases stress resilience
Inverse
In times of serious stress, people might turn to exercise to blow off steam and shake off nervous energy. However, despite anecdotal evidence, the link between working out and relieving stress isn't well understood by scientists. Researchers haven't yet pinned down exactly how exercise modulates stress in the brain and body, despite knowing that exercise benefits mental health.
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Short exercise breaks during class improve concentration for senior students
Study International News
Primary school teachers often provide students with short physical activity breaks to energize kids and minimize classroom disruptions. Our study, published in the journal Educational Psychology Review, found we should be doing this for senior students too. We found a short activity break can improve students’ focus on the task at hand and make them feel more energized.
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Study: Choose nutrient dense whole plant-based foods for a healthy diet
Green Queen
A new study finding variable nutritional quality of different plant foods highlights that not all plant-based options are “created equal” and that replacing meat consumption with whole plant foods is the best way to ensure a healthy diet.
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VITAMINS & PHARMACEUTICALS
 
 
Best vitamins for kids: Diet, considerations and more
Medical News Today
A well-balanced diet provides nutrients essential for children’s growth and development. However, children who eat a limited diet or are less able to absorb or make certain nutrients may need supplements.
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Lack of vitamin D might increase risk for COVID-19, University of Chicago researchers find
Chicago Tribune
A lack of vitamin D may be associated with a higher risk for getting COVID-19, according to newly published research out of the University of Chicago. Researchers looked at 489 patients tested for COVID-19 at University of Chicago Medicine between March 3 and April 10, whose vitamin D levels had been measured within a year of being tested for COVID-19.
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What's the relationship between low levels of vitamin B-12 and depression?
Medical Xpress
Vitamin B-12 and other B vitamins play a role in producing brain chemicals that affect mood and other brain functions. Low levels of B-12 and other B vitamins such as vitamin B-6 and folate may be linked to depression.
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NAMCP UPDATES
 
 

LivaNova PLC, a market-leading medical technology and innovation company, today announced the publication of a new study in the International Journal of Bipolar Disorders that showed adding Vagus Nerve Stimulation Therapy (VNS Therapy®) to treatment as usual (TAU) significantly improves outcomes in patients with treatment-resistant bipolar depression (TRBD). The study examined patients from a five-year prospective registry and found 63% of TRBD patients treated with adjunctive VNS Therapy in addition to TAU had a significant reduction in depressive symptoms, as measured by a 50% or greater reduction in the Montgomery–Åsberg Depression Rating Scale (MADRS), compared with 39% of patients in the TAU alone group. Click here to view the entire press release. Click here to view the entire press release.


Additionally, LivaNova PLC announced a publication in Contemporary Clinical Trials, which details the design for “A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression” or the RECOVER clinical study. RECOVER is currently under way as part of a Coverage with Evidence Development framework of the U.S. Centers for Medicare & Medicaid Services’ (CMS) National Coverage Determination process. Click here to view the entire press release.


In late 2018, the National Association of Managed Care Physicians (NAMCP) decided to create the Value Based Care Council (VBCC). The VBCC mission supports empowering medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. The goal is to improve the integration of cost, quality, and access in the clinical decision making process so as to enhance the effectiveness and efficiency of extracting value from the associated spend in order to optimize outcomes.

Pursuant to the above, and in response to an unmet need in the marketplace, the VBCC developed a short form in order to enhance the effectiveness and efficiency with which value propositions can be shared between industry and the medical leadership of various payers throughout the country. This same short form provides a concise and consistent manner with which value propositions can be shared and provides the ability to align expectations prior to actually conducting conversations or having a meeting regarding a product or service.

The Product Value Proposition Customer Engagement Short Form can be found on the NAMCP website (www.namcp.org) in the Value Based Care Council subsection of the Councils tab, under tools and resources. Please contact Will Williams at wwilliams@namcp.org with questions or for additional information.


Jazz Pharmaceuticals is excited to announce the approval of ZEPZELCA™ (lurbinectedin) for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. ZEPZELCA is a second-line therapy that has been studied in both platinum-sensitive and -resistant SCLC patients. Please click here for more information.


Takeda Pharmaceuticals is part of, "The Fight Is In Us", an initiative to maximize the individual and societal benefit of COVID-19 plasma. The campaign will focus on recruiting COVID-19 survivors to donate their plasma at licensed blood and plasma donor centers.
  • If you’ve recovered from #COVID19, your immune system has antibodies that could be used as a treatment. See if you can help others by donating plasma www.TheFightIsInUs.org. #TheFightIsInUS

  • The antibodies that helped you or someone you know fight off COVID-19 may be able to help others. Visit www.TheFightIsInUs.org to see if you qualify to donate plasma. #TheFightIsInUs
You are a survivor, now you could be a hero. Plasma from recovered #COVID19 patients could play a key role in creating a potential therapy for coronavirus. Learn how you can donate at www.TheFightIsInUs.org #TheFightIsInUs


Biodesix, Inc., a leading diagnostic company in lung disease, recently announced a partnership with Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) to bring a COVID-19 Droplet Digital PCR (ddPCR) test to the FDA for an Emergency Use Authorization (EUA) approval to support the escalating need for testing in the U.S. Two studies published this month, ahead of peer review, reported that ddPCR testing showed superior sensitivity and precision for clinical detection of SARS-CoV-2 (the virus that causes COVID-19) compared to existing test methods that are performed using qPCR. Biodesix currently has a focus on lung disease and offers other diagnostic testing for lung cancer utilizing the ddPCR platform.Click here for more information.


"Modeling Cost-Effectiveness of On-Demand Treatment for Hereditary Angioedema Attack" was recently published in the Journal of Managed Care Pharmacy's February 2020 issue. Hereditary angioedema (HAE) is a rare disease that causes painful and potentially fatal episodes of swelling (attacks). HAE attacks can be unpredictable and the need to treat sudden attacks promptly and effectively is critical to minimize risk of hospitalization, morbidity, and mortality. A cost-effectiveness model was evaluated that considers evaluation of on-demand medications, healthcare utilization and patient well-being. For access to the publication, please click here.


Biodesix, Inc. announced initiation of the next phase of their biomarker development program with Merck KGaA, Darmstadt, Germany and Pfizer Inc. The companies have completed initial discovery and development of a new proteomic test that identifies likely responders to the anti-PD-L1 checkpoint inhibitor (BAVENCIO®) (avelumab). Development efforts will now focus on transferring the test into Biodesix's CLIA lab in Boulder, CO for clinical phase test validation. The new test was developed through retrospective analysis of the circulating proteome of cancer patients treated with the investigational drug candidate, utilizing the proprietary Biodesix Diagnostic Cortex™ artificial intelligence (AI) platform. Click here to read the full press release.


The NAMCP Medical Directors Institute recently held the first meeting of its Executive Leadership Council (ELC) at the recent Fall Managed Care Forum. The NAMCP Medical Directors Institute decided in late 2018 to create the Value Based Care Council (VBCC) with a mission to empower medical directors with information and resources to assist them in making value based decisions that support achieving the Triple AIM of improved outcomes and the patient experience while reducing overall costs. Click here to view an overview of the genesis, formation, and work of NAMCP's Value Based Care Council. Please click here to view the press release.


LivaNova PLC (NASDAQ:LIVN), a market-leading medical technology and innovation company, today announced the first patient enrolled in "A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression" (RECOVER). The study will evaluate Vagus Nerve Stimulation Therapy (VNS Therapy) for Treatment-Resistant Depression (TRD) in accordance with the U.S. Centers for Medicare & Medicaid Services (CMS) National Coverage Determination as part of its Coverage with Evidence Development Program. The first patient was enrolled by Dr. Azfar Malik in St. Louis. Click here to read the full press release.


Biodesix, Inc. this week highlighted findings from multiple studies demonstrating the significance and clinical utility of its VeriStrat® blood-based proteomic test as a predictive biomarker for patient survival outcomes and as a diagnostic tool to improve the clinical management of patients with non-small cell lung cancer (NSCLC). This information is vital to implementing optimal treatment strategies for patients and supports disease state monitoring. To date, VeriStrat testing has helped more than 50,000 patients in determining the best treatment for their lung cancer. Click here to see the full press release.
 
 
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