SLAS Point-to-Point
Dec. 28, 2016

Shana Kelley Earns 2016 SLAS Innovation Award
From Feb. 3: Shana Kelley of the University of Toronto took home top honors and a $10,000 check for her SLAS2016 scientific presentation, "New Devices for the Detection and Classification of Antibiotic-Resistant Bacteria." Kelley described her team's work to develop new electrochemical tools for direct molecular analysis of bacteria — some in less than 30 minutes — and the potential clinical applications of these tools. In addition to the cash award, Kelley receives a one-year SLAS membership, is invited to have her work featured in either JALA or JBS and joins the judging panel for the 2017 SLAS Innovation Award.More

Select SLAS2016 Presentations Now Available On Demand
From Feb. 10: Seven podium presentations were recorded at SLAS2016 and are now available on-demand by full conference registrants (until March 31, 2016) and dues-paying SLAS members.

HT-MALDI-MS as a Complete Label-Free Drug Discovery Platform: From Target Characterization through High-Throughput Screening to Hit Follow Up (Scott Busby, Novartis Institutes for Biomedical Research, USA)

Development of a Platform to Enable Fully Automated Cross-Titration Experiments (Jason Cassaday, Merck, USA)

Identifying Druggable Cells: Automated Methods for High-Content Single-Cell Screening (Tiffany Chen, Cytobank, Inc. and Stanford University, USA)

High-Throughput Screening of Metagenomic DNA Libraries (Louis Cohen, Icahn School of Medicine at Mount Sinai, USA)

Genome Engineering with Zinc Finger Nucleases (Ed Rebar, Sangamo BioSciences, USA)

Droplet Microfluidics: Amphiphilic Nanoparticles as Droplet Stabilizers for High-Fidelity and Ultrahigh-Throughput Droplet Assays (Sindy Tang, Stanford University, USA)

Drug-Target Residence Time: Target Engagement, Target Vulnerability and Predictions of in Vivo Drug Activity (Peter Tonge, Stony Brook University, USA)More

SLAS ELN Reports: Shaking Up 3D Culture — Novel Systems Agitate Cells to Facilitate Cell-Based Screening
From Aug. 24: For life sciences discovery and technology professionals, working with 3D culture has numerous advantages, including emulation of the in vivo environment; high cell yields from less laboratory space; and a significant reduction in costs of labor and consumables. That's the word from Robin Felder, Ph.D., professor and associate director of clinical chemistry and toxicology at the University of Virginia School of Medicine.

Read more from Felder and Lee L. Rubin, Ph.D., Harvard Department of Stem Cell and Regenerative Biology, in the SLAS Electronic Laboratory Neighborhood e-zine feature article.More

New and Free at JALA Online: Automated Gravimetric Calibration to Optimize the Accuracy and Precision of TECAN Freedom EVO Liquid Handler
From June 22: HTS technologies are increasingly integrated into the formulation development process of biopharmaceuticals. The performance of liquid handling systems is dependent on the ability to deliver accurate and precise volumes of specific reagents to ensure process quality.

A collaborative team from GSK Vaccines (Belgium) and Neomed Institute (Canada) has developed an automated gravimetric calibration procedure to adjust the accuracy and evaluate the precision of the TECAN Freedom EVO liquid handling system.

Read more in JALA from authors Laurent Bessemans, Vanessa Jully, Caroline de Raikem, Mathieu Albanese, Nicolas Moniotte, Pascal Silversmet and Dominique Lemoine.More

Congratulations to SLAS Tony B. Academic Travel Award Winners!
From Oct. 26: 62 students from 15 countries will travel to SLAS2017 to present their scientific work Feb. 4-8 in Washington, DC. 11 of these students will deliver podium presentations and 51 will make poster presentations, including 4 students who were recognized as top poster presenters from SLAS Europe events earlier this year. Tony B. winners receive roundtrip travel, shared hotel accommodations and full conference registration.

The Tony B. Academic Travel Awards honor the late Tony Beugelsdijk, Ph.D., an inspirational and iconic leader in the field of life sciences discovery and technology who made an extraordinary impact on the SLAS community.More

Now Online: SLAS2016 Keynote Presentation 'Analyzing the Complexity of Drug Resistance in Cancer'
From Feb. 17: The SLAS2016 opening keynote presentation by NIH Deputy Director for Intermural Research Michael M. Gottesman, M.D., is available on demand free-of-charge to the general public.

In addition, seven podium presentations from SLAS2016 are now available as on demand webinars for dues-paying SLAS members. Join or renew your membership to access immediately.More

Meet 'The 2016 JALA Ten'
From March 30: "Each year, JALA seeks to highlight and honor the very best work of the year that will have a deep impact on how technology is used across a wide range of disciplines," says JALA Editor-in-Chief Edward Kai-Hua Chow, Ph.D., of the National University of Singapore. "While a number of areas of research will feel the impact of this year's JALA Ten, one highlight of the collection is the diverse ways in which the honorees have advanced biological molecule detection and established foundations for tomorrow's biosensors in life sciences research and medical diagnostics."

Read about the 10 honorees in the April 2016 issue of JALA.More

Eight Exciting Entrepreneurs Earn Invitations to SLAS2017 Innovation AveNEW
From Dec. 7: These promising new start-up companies kick off 2017 by bringing their novel technologies to the SLAS2017 Exhibition. Selected by a panel of judges from a pool of impressive applicants, these SLAS Innovation AveNEW entrepreneurs earn complimentary exhibit space, travel, hotel and conference registration; all to put them and their scientific innovations face-to-face with the world-class professionals at SLAS2017 in Washington, DC, Feb. 4-8. Congratulations to:


SLAS ELN Reports: Michelle Arkin — All Things are One Thing
From March 2: SLAS2016 Drug Target Strategies Track Chair Michelle Arkin, Ph.D., likes a good puzzle. Not only does she enjoy deciphering complicated connections and matching up contrasting ideas, she refers to it as her "personality super power." Even more powerful to her is the sharing of ideas between like-minded professionals in the life sciences discovery and technology community.

Read more about the associate professor in pharmaceutical chemistry and associate director of biology in the Small Molecule Discovery Center at the University of California, San Francisco and an author of several JBS papers in the SLAS Electronic Laboratory Neighborhood.More

Fernanda Ricci Wins 2016 JALA & JBS Art of Science Contest
From Feb. 24: Congratulations to Fernanda Ricci of IIT@SEMM in Italy, top vote-getter and winner of a $500 Amazon gift card for her beautiful image — a mosaic representation of cell colonies and the resulting automated segmentation obtained with Colony Assay Toolbox (CaT, F. Ricci et al. JBS 2014).

The illustrations are representative of a colony formation in a 384 multi-well format; the single wells are entirely acquired by using a 4x objective combined with a large camera in wide-field microscopy (Nikon Ti-Eclipse). All 10 finalists receive 60 days free online access to the SAGE Pharmacology & Biomedical Collection (100,000+ research reports!).More